Sentence examples for mutations affects the from inspiring English sources

None of the mutations affects the Usa1-Der1 interaction (Figure 4E).

To understand whether inactivation of BRCA1 by germline mutations affects the TGF-β signaling pathway, we investigated the effect of BRCA1 mutations on TGF-β1 transactivation activity by performing a cell-based reporter assay with a TGF-β-responsive reporter, p3TP-Lux [19].

None of these deletion mutations affects the ciliary localization of Smo (Supplementary Material, Fig. S1).

Each of the N-terminal mutations affects the intracellular stability, dimerization, and in vivo function of TraJF, suggesting that these features of TraJF are intrinsically related.

The majority of cancer-related PTPRT mutations affects the extracellular domain that mediates homophilic cell cell interactions, suggesting that mutation of this phosphatase supports tumor migration [ 159].

Furthermore, we demonstrated that the reduction of KMT2D protein level in patients' lymphoblastoid and skin fibroblast cell lines carrying KMT2D-truncating mutations affects the expression levels of known KMT2D target genes.

But what interests him most is homing in on the mutations affecting the cilia.

Working with the geneticist L. C. Dunn and others, Dr. Waelsch described mutations affecting the spine and skeleton and observed other inherited abnormalities as they appeared.

All mutations affected the FBXW7 target interacting domain.

We demonstrated that most mutations affected the activity of HtrA.

Fig. 2 Possible consequences of migraine mutations affecting the central glutamate synapse.