Sentence examples for mutations affecting other from inspiring English sources

Genetic heterogeneity has been confirmed in rare sporadic cases, with mutations affecting other postsynaptic glycinergic proteins including the GlyR β subunit (GLRB 4, gephyrin (GPHN 5 and RhoGEF collybistin (ARHGEF9 6.

There are reports of mutations affecting other portions of the mtDNA including cytochrome b or mitochondrial encoded tRNAs in isolated cases of SA [16], [17], [18], [19].

First, mutations affecting other DNA polymerases might alter induction of the SOS DNA-damage response, and so indirectly affect expression of dinB, which is required at SOS-induced levels for mutagenesis [38], thereby affecting Pol IV-dependent mutagenesis.

This indicates that mutations affecting other GNAS transcripts, in particular XLαs, can also produce significant effects.

Accordingly, we examined the effect on Rad51 binding of mutations affecting other putative phosphorylation sites in GgBrca2.

This effect is not seen with mutations affecting other enzymes in the proanthocyanin biosynthetic pathway, implying a link between proanthocyanin biosynthesis and vacuole development.

However, we could not confirm if the SPL5 gene mutation affects other biological pathways that trigger similar phenotypes.

However, we cannot rule out that the mutation affects other loci which control floral organ number in a RhAG-independent manner.

Thus, mutations or alterations affecting other mechanisms must underlie the Warburg effect in many cells.

However, all patients inevitably develop acquired resistance to these agents, primarily due to secondary EGFR mutations, molecular aberrations affecting other signaling pathways, or transformation to small-cell histology.

As p300 interacts with many other TFs, we were mindful that this p300 mutation might be affecting other KIX-dependent interactions, most notably with the CREB family of TFs.