Sentence examples for mutations affecting early from inspiring English sources

Our forward genetic screens in zebrafish for recessive mutations affecting early T cell development revealed several major genetic pathways.

We performed a clonal genetic screen on the left arm of chromosome 2 for mutations affecting early oogenesis.

Specifically, we aimed to determine whether these mutations affect early and/or late events of the virus replication cycle.

We used the same comparison to determine whether the Y16A, C18S, and NoCys mutations affect early- or late-stage photoaggregation.

Another study using C57BL/6 mice showed that CXCR3 mutation affected early granuloma formation after aerosol M. tuberculosis infection and correlated this with the invasion of polymorphonuclear neutrophils that produce chemokine signaling via CXCR3 (Seiler et al., 2003).

The recovered mutations defined 315 independent mutants affecting early development.

The missense mutation in GGA4 that located on NCAPG was posterior putative locus for its roles in affecting early eggshell weight.

After 2 weeks, the length of newly emergent roots is normal relative to the wild type, suggesting that this mutation specifically affects early root growth.

The ER + IDC pathway tends to be activated by early mutations affecting the anti-apoptotic (pro-survival) PI3K signaling pathway; the commonest such mutation affects the PTEN gatekeeper gene, permitting secondary ER-α and ER-β upregulation, leading in turn to Snail induction, EMT-related TGF-β and Wnt pathway activation, BRCA1/2 and/or TP53 inactivation.

Furthermore the co-variance of other characters, such as the appearance of a sh connection can be regarded as an example of how mutations affecting the regulation of an early morphogenetic process can lead to the co-evolution of many characters of the same organism, that are presumed not to be functionally related.

Indeed, mutations affecting OTX2 protein coding sequence have early and severe effects on brain and eye development [14], [24].