Sentence examples for mutations affecting diverse from inspiring English sources

These syndromes are caused by gene mutations affecting diverse cellular pathways but all resulting in premature failure of hematopoiesis.

(1) Disease-causing TRPV4 mutations affect diverse regulatory mechanisms, converging to bone or neuron-related phenotypes in how they ultimately affect TRPV4 activity.

Mutations in LMNA encoding lamins A and C are associated with at least 10 different degenerative disorders affecting diverse tissues, collectively called laminopathies.

Our bioinformatics approach undertaken in this study provides a new insight as to how a single gene mutation may affect diverse molecular functions, such as RNA metabolism, translation initiation, and cytoskeletal dynamics leading to complex disease.

Maize (Zea mays L). has a long history of genetic research, and consequently a diverse collection of mutations affecting a broad range of biological processes has accumulated (Neuffer et al., 1997).

Consequently, mutations affecting the function of MICOS are responsible for a diverse spectrum of human diseases.

But what interests him most is homing in on the mutations affecting the cilia.

We hypothesise a higher frequency of mutations affecting smokers.

Mutations affecting the DGC cause muscular dystrophies.

Hence, mutations affecting mitochondrial structure also affect metabolism.

However, taken together with a recent report that mutations affecting the epigenetic factor SETD2 are associated with loss of histone H3 lysine 36 tri-methylation (H3K36me3) and increased intron retention in clear cell renal cell carcinoma [ 19], our results suggest that crosstalk between epigenetics and RNA splicing may link a diverse spectrum of mutations to RNA processing defects in cancer.