Sentence examples for mutations affecting both from inspiring English sources

They analyzed the genome sequences of 11 RS index subjects from eight different families, and reported pathogenic mutations affecting both SLCO1B3 and SLCO1B1.

In contrast, all the mutants were found to have altered NADH ferricyanide reductase (NADH FR) activity with mutations affecting both kcat and KNADHm, which decreased and increased, respectively.

This would be in agreement with the observation that, even in mutant 8/K which contains three mutations affecting both sections of the C-terminal NLS, partial nuclear localisation is detected (Fig. 2B,C).

Mutations affecting both 1-8-14 1-8-14 1-8-14ntroduced in a GST-fusion of the N-termotifssegment AA 147–209 of rEAG1 in order to localize the residues needed for the interaction were CaM and to determintroducedh motins are fully functional.

In fact, we found and validated mutations affecting both splicing machinery and epigenetic genes.

Interestingly, regarding GRIN2C, GRIN3A and GRIN3B, only rare truncating mutations affecting both healthy individuals and ASD/SZ patients have been reported.

As the results suggest that heterogeneity in RB1 mutations affect both the penetrance of retinoblastoma and likely tumor progression [66] it stresses the importance of analyzing parents with hereditary forms of retinoblastoma.

This raises the possibility that structural changes imposed by these mutations affect both snRNP assembly and calpain cleavage.

Two missense mutations affect both GDH1 and MAL11.

While the A94fs199X and Y236S mutations affect both SynIIa and SynIIb isoforms, the G464R mutation affects SynIIa only.

Shaker2 mutations affect both isoforms and lead to short hair bundles.