Sentence examples for mutations affect ubiquitin-binding from inspiring English sources

The I424S and A427D SQSTmutationsons affect ubiquitin-binding and NF-κB signalling.

Surprisingly, these mutations also affected ubiquitin-binding, suggesting that they have a broad effect on UBXN7 function, possibly by altering the overall structure of the protein.

As the parkin mutations affect a ubiquitin E3 ligase, the field focuses on proteasome inhibition, attempting to identify parkin's substrates and to nominate the toxic species.

Two in-frame insertion mutations affect the phosphate-binding loop (codon 10 16) of KRAS are identified.

These mutations affect the DNA-binding stability of WT1 to the target gene [ 73].

Mutations affect individual genes or binding sites or stretches of genome.

We examined whether NR2E3 mutations affected DNA-binding.

SNAP identified mutations altering agonist binding and expression better than mutations affecting antagonist binding and constitutive activity (Supplemental Table 2).

Here we report that a group of mutations affecting various ubiquitin-conjugating enzymes cause significant GSCs loss, including Plenty of SH3s (POSH ), Ubiquitin-conjugating enzyme 10 (UbcD10 ), and pineapple eye (pie ).

Most p53 mutations were hemizygous missense mutations affecting the DNA-binding domain of p53.

The major cause of RTT are mutations affecting the methyl-CpG binding protein 2 (MEcodingodingenene [1].