Sentence examples for mutations affect a from inspiring English sources

Thus, it is possible that these mutations affect a common active site.

Moreover, whereas point mutations affect a single nucleotide base, CNVs affect many, with multiple genes sometimes affected by a single CNV.

Furthermore, while natural variation SNP are shared by multiple individuals and can thus be confirmed through biological replication, most mutations affect a single individual.

As the parkin mutations affect a ubiquitin E3 ligase, the field focuses on proteasome inhibition, attempting to identify parkin's substrates and to nominate the toxic species.

Given that these mutations affect a critically important region of the protein (Bonn et al., 2010), they are highly likely to be pathogenic.

The way to reach a higher fitness is then to decouple mutation effects such that mutations affect a subset of phenotypes and not all.

By analogy to the extensive literature on mutators (and antimutators) in bacteria and yeast, mutations affecting a broad range of processes that impinge on the mutation rate could be responsible for the extensive variation in mitochondrial mutation rates in Geraniaceae.

Conceptually, an accumulation of mutations affecting a number of genes affecting disease specific pathways may establish a genetic liability gradient for schizophrenia where a critical threshold is required for the manifestation of the disease state [54].

To further study this phenomenon, different cells carrying mutations affecting A or S motility were placed on polystyrene surfaces in 1% methylcellulose-containing medium.

In contrast, mutations affecting a single residue by substitution or deletion were more frequent among sltB mutations.

Many autosomal Mendelian disease phenotypes can be understood in terms of dominant and recessive mutations affecting a particular gene.