Sentence examples for mutations acquired by from inspiring English sources

Knowing the mutations acquired by mutH5N1, they could simply alter ordinary H5N1 viruses at the same sites in its genes to match it.

The mutations acquired by the human homolog of PCNA relative to the yeast homolog preserve the existing three dimensional structure but reduce its stability and folding cooperativity and increase the local backbone dynamics.

The list of coding mutations acquired by the strain lineage of P. chrysogenum.

This is the first study to report the mutations acquired by second line failure patients in the National program.

Infection with passaged bacterial clones revealed the phenomenon not to bedue to adventitious mutations acquired by the pathogen.

We put forward a possible role of stochastic effects on the generation and fate of mutations acquired by stem cells.

The current explanation for the development of therapy resistance and tumour recurrence invokes genomic alterations and selection of mutant cells carrying a relevant mutation acquired by chance before therapy (Nowell, 1976; Yachida et al, 2010; Sottoriva et al, 2013).

The only other mutations acquired in common by 1974M1 and at least one of these other mutants were a G to T transversion in the promoter regions of the ATP-binding cassette (ABC) genes spr1887 and spr1021 (Table 2, Figure 1).

The model is illustrated schematically in Figures 6 and 7. Cells at different stages of the process are labelled by I α, β, d ), where the first subscript, α, represents the number of cancer stage mutations that the cell has accumulated, the second subscript, β, represents the number of destabilizing mutations acquired, their type being given by the third subscript, d.

Let P(M j) represent the Poisson probability of the set of M mutations that were acquired by genotype G in generation j: m j,1 mutations acquired in class 1 at rate U1, m j,2 in class 2 at rate U2, and so on for j = 1 though k.

Two criteria were used to identify unique mutations possibly acquired by these sequences after their insertion into the nuclear genome: (i) such unique mutations are unknown in mtDNA of other species and (ii) they have functional effects on encoded mitochondrial proteins.