Sentence examples for mutations accumulated in from inspiring English sources

With spontaneous mutations accumulated in the mutator strain P. fluorescens ATCC948 for almost 2 years, we have established the base-substitution mutation rate of this strain to be 2.34 × 10− per site per generation, dominated by AT → GC transitions.

We searched for such effects in the abundant base-substitution mutations accumulated in this mutator strain (1,537 base substitutions occurring on potential methylation target sites of Dam/Dcm/EcoKI/EcoBI/HgiDII were excluded to avoid mutation rates being complicated by methylation, as methylation sites are known mutational hotspots; supplementary table S7, Supplementary Material online).

However, the amount of mutations accumulated in both groups for the different mutational categories (nonsynonymous, synonymous, tRNA, and recurrent, among others) was statistically non-significant in all cases (Pearson's chi-square test, p-value>0.05).

Mutations accumulated in genes which normally are rarely or non-expressed or non-mutating.

Three separate point mutations causing three independent amino acid changes (nonsynonomous mutations) accumulated in the same sequence and enriched throughout the selection protocol, suggesting that these changes confer binding advantages.

By examining some 450 somatic mutations accumulated in non-repetitive genome sequences from the blood of a healthy 115-year old woman, the mass of mutations observed were harmless mutations suggesting that "the finite lifespan of hematopoetic stem cells (HSCs), rather than somatic mutation effects, may lead to hematopoietic clonal evolution at extreme ages" [39].

However, there is an important trade-off to consider, as an increased mutation rate will come at the cost of increased mutational load [ 52], in which the random deleterious mutations accumulate in the genome, conferring a large fitness cost.

Not having sex means this cannot happen, so mutations accumulate in each asexual line.

As time passes, mutations accumulate in the DNA, as one "letter" of the genetic code is replaced by another.

Since the silent mutations accumulate in a random but steady fashion, they serve as a molecular clock, one that started ticking at the time of the last sweep of the MC1R gene through the ancestral human population.

2) We should pay special attention to spontaneous mutations accumulating in seeds.