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Finally, using truncation mutations, a potential domain of DGAT1 that was involved in the regulation of enzymatic activity was revealed.
Similarly to EGFR mutations, a potential effect of ALK translocation on checkpoint expression cannot be excluded and additional studies are recommended in this particular NSCLC subpopulation.
In a recent meta-analysis showing a favorable clinical outcome in ERα-positive postmenopausal breast cancer patients with PIK3CA kinase domain mutations, a potential favorable response to endocrine treatment was suggested as one of the explanations [ 46].
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The smaller intergenic regions in L. thermotolerans provide fewer targets for mutation, a potential explanation for a lower mutation rate.
Also, the group of Fukai (Osaka, Japan) has suggested the use of aminoglycosides, known to allow the read-through effect over certain nonsense mutations, as a potential therapeutic intervention for some mutations commonly found in albinism [ 83].
In addition, a few PZ-resistant strains with no PZase activity did not have pncA mutations, indicating a potential regulatory gene of pncA that may have acquired a mutation.
Thus, it can be confirmed that this mutation is a potential pathogenic mutation.
These modifications are possible by single point mutations, suggesting a potential yield of a more infectious virus.
He envisions a day when a device implanted in your body will be able to identify the first mutations of a potential tumour, or the genes of an invading bacteria.
Additional studies have suggested that MEFV rare missense causative mutations have a potential modifying effect in IBD patients [27] [30].
Thus, the presence of tumor-specific mutations provides a potential link to predicting methylation status.
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CEO of Professional Science Editing for Scientists @ prosciediting.com