Sentence examples for mutations a characteristic from inspiring English sources

All of these strains carry multiple mutations, a characteristic of fragile phenotypes.

Cancers with BRCA1 or BRCA2 mutations exhibited a characteristic combination of substitution mutation signatures and a distinctive profile of deletions.

The only patient with identified pathogenic mutations had a characteristic clinical presentation (reversible liver disease) that guided the genetic analysis and led to the identification of mutations in TRMU.

Two recurrent tumors treated with temozolomide (TMZ) had an enormous number of somatic mutations with a characteristic signature and were considered to be TMZ-induced hypermutators (Fig. 5a 13.

Since 98% of retinoblastomas have RB1 mutations and a characteristic genomic copy number "signature", genetic analysis is an appealing adjunct to histopathology to distinguish retinoblastoma metastasis from second primary cancer in retinoblastoma patients.

DSiaT mutations cause a characteristic temperature-sensitive paralysis phenotype (TS paralysis) (Repnikova et al. 2010).

The TP53 mutation status showed strong association with the 'basal-like' and 'ERBB2+' subgroups, and tumors with mutation had a characteristic gene expression pattern.TP53 mutation status and gene-expression based groups are important survival markers of breast cancer, and these molecular markers may provide prognostic information that complements clinical variables.

Each mutation had a characteristic melting profile that would allow it to be identified by using a control for that mutation.

While variability exists, most cases with this mutation have a characteristic spectrum of demographic, clinical, neuropsychological, neuroimaging and especially neuropathological findings.

In fact, the identified phytoene synthase 1, which catalyzes a rate-limiting step in the carotenoids pathway, corresponds to the locus " r" [ 34] that carries a recessive mutation conferring a characteristic yellow flesh phenotype.

Tumor samples carrying the A908G mutation produced a characteristic band shift on SSCP, similar to that exhibited by the positive control benign breast tissue, as shown in Fig. 1a.