Sentence examples for mutational variant in from inspiring English sources

The fact that these variants are frequently stored in the database does not mean that they are mutational hotspots, but rather reflects the inheritance of the corresponding mutational variant in European matrilines.

In summary, the mutational variants in CD further describe a defect in bacterial sensing, as mentioned by Wagner et al, 9 and an exaggerated response of the intestinal immune system.

The catalytic efficiency of the mutational variant used in the study is highlighted in bold for easy reference, and additional mutants are listed in Appendix 1 Table 1.

A particularly interesting mutational variant present in the sequenced strain is the insertion of a Doc transposable element in the C HKov1 gene (CHKov1 Doc1420 ).

The exploration of mutational landscapes is an important step in understanding differences between amyloid topologies, how mutational variants arise in the wild, and to elucidate evolutionary relationships between related amyloid proteins.

However the SD mutational variant was fully defective in increasing actin assembly at the protruding leading edge and FA assembly/disassembly rates, indicating that SD phosphorylation is the sole p130Cas signaling function in regulating these processes.

Whether other IDH1 or IDH2 mutational variants exist in GTNI and whether a genotypic restriction to IDH1 R132H alone would have any functional significance remain unclear.

S-----IQ is found in nearly all 8q13.4 genes (only ZNF7 has the mutational variant R-----IQ).

Using this lentivirus system, we generated stable THP-1 cell lines with promoters containing WT HIV, P-selectin, and Skp2-κB sites or their mutational variants, and measured dGFP expression in LPS-stimulated cells.

Cas −/− MEFs stably expressing WT p130Cas versus mutational variants (Fig. 1A) were generated in order to evaluate the contribution of p130Cas signaling domains to cell migration.

The loss of coordination among these parameters together with the influence of habitat contamination and degradation may generate differences in sets of mutational variants and influence their frequencies [56].