mutational status of

USAGE SUMMARY

The phrase "mutational status of" is correct and usable in written English.
It can be used in contexts related to genetics, biology, or medical research when discussing the specific mutations present in an organism or sample. Example: "The study focused on the mutational status of the tumor to determine the best treatment options."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

In the only case with HRAS mutation, the mutational status of PIK3CA was indeterminate.

BMC Cancer

The mutational status of sixty-four comutatedmutated cancer genes was assessed.

BMC Genomics

We apply our method to data obtained by interrogating the mutational status of p53 in 50 cancer cell lines (33 mutated and 17 normal).

Stanford University

Data matrix showing the mutational status of known cutaneous SCC-driver genes.

Nature

It is important to not just determine the CN status of 17p, but also determine the mutational status of TP53.

Nature

Metabolic heterogeneity of human tumors is dependent upon the mutational status of specific oncogenes and influenced by tumor microenvironment.

Seminars in Cell & Developmental Biology

One crucial parameter for prediction of treatment response is the mutational status of the EGFR.

EJNMMI Radiopharmacy and Chemistry

These hurdles have urged the pursuit of alternative, non-invasive approaches for evaluating and quantifying the mutational status of EGFR [15,16].

EJNMMI Research

[11C]erlotinib has been proposed as a PET tracer to visualize the mutational status of the epidermal growth factor receptor (EGFR) in cancer patients.

EJNMMI Radiopharmacy and Chemistry

Interestingly, the synergistic cytotoxicities identified did not correlate with the known oncogene RAS and RAF mutational status of the melanoma cell lines.

Journal of Cheminformatics

For non-small cell lung cancer (NSCLC), the effectiveness of TKIs is dependent on the mutational status of epidermal growth factor receptor (EGFR).

EJNMMI Research

Expert writing Tips

Best practice

When discussing cancer treatment options, specify the gene associated with the "mutational status of" to provide precise and actionable information for clinicians.

Common error

Avoid using "mutational status" when you actually refer to gene expression levels. "Mutational status" indicates the presence or absence of mutations in a gene, while gene expression refers to the amount of mRNA or protein produced from that gene. They are distinct concepts.

Linguistic Context

The phrase "mutational status of" functions as a noun phrase acting as a subject or object of a sentence. It identifies the presence or absence of mutations in a specific gene or region of DNA, a fact confirmed by the Ludwig AI.

Expression frequency: Very common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

The phrase "mutational status of" is a grammatically sound and frequently employed term, especially in scientific and medical fields. As verified by Ludwig AI, it serves to describe the presence or absence of mutations in a particular gene, commonly within the context of cancer research and personalized medicine. With a very common usage frequency, this phrase is most often found in science-related contexts. Alternatives such as "mutation profile of" or "genetic alteration status of" can be used depending on the specific nuance you want to convey. When using the phrase, clarity is key: always specify the gene you're referring to.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

mutation state of

Replaces "status" with "state", a direct synonym in this context.

mutational profile of

A slight variation of "mutation profile of", emphasizing the mutational aspect.

genetic mutation status of

More explicit by adding the word "genetic" before mutation.

mutation profile of

Focuses on the comprehensive pattern of mutations rather than just the state.

genetic alteration status of

Broader term encompassing all types of genetic changes, not just mutations.

genomic mutation profile of

Highlights the genomic aspect of the mutation profile.

mutational landscape of

Implies a comprehensive view of all mutations present.

mutation analysis of

Emphasizes the analytical aspect of studying mutations.

mutation characteristics of

Focuses on the specific attributes and properties of the mutations.

mutation load of

Focuses on the quantity or burden of mutations.

FAQs

How is the phrase "mutational status of" typically used in scientific writing?

The phrase "mutational status of" is commonly used in scientific writing to describe whether a specific gene or region of DNA contains a mutation or is wild-type (non-mutated). It often appears in the context of cancer research and personalized medicine, where knowing the mutational status of certain genes can inform treatment decisions.

What are some alternatives to using "mutational status of" in a research paper?

Depending on the specific context, you could use alternatives such as "mutation profile of", "genetic alteration status of", or "mutation state of". For example, instead of saying "the mutational status of EGFR was determined", you could say "the "mutation profile of" EGFR was determined".

Is it important to specify which gene is being referred to when discussing "mutational status of"?

Yes, it's crucial to specify the gene when discussing the "mutational status of" because the presence or absence of mutations can have different implications depending on the gene involved. Being specific ensures clarity and avoids ambiguity in your writing.

How does knowing the "mutational status of" a gene impact treatment decisions in cancer?

The "mutational status of" certain genes can predict a patient's response to specific therapies. For instance, certain EGFR mutations in lung cancer make patients more likely to respond to EGFR inhibitors. Therefore, determining the "mutational status of" these genes helps personalize treatment strategies.