Sentence examples for mutational spectrum within from inspiring English sources

However, the mutational spectrum within some of the genes is clearly different.

The aim of this study was to successfully identify Lynch syndrome families and to report the MLH1, MSH2 and MSH6 mutational spectrum within Greek colorectal cancer families.

PAX6 allelic heterogeneity in Mexican congenital aniridia patients: expanding the mutational spectrum with seven novel pathogenic variants.

H. volcanii has an unusual mutational spectrum with a prevalence of in-frame indels flanked by direct repeats [5].

Further studies in other populations are warranted to determine more accurately the frequency of the SQSTM1/P392L mutations at a germinal, post-zygotic and somatic level, respectively, and to determine how post-zygotic mutations, within the SQSTM1/P392L mutational spectrum, may contribute to the focal nature of pagetic bone involvement.

Inactivation of nucS in M. smegmatis produces specific phenotypes that mimic those of canonical MMR-null mutants (increased mutation rate, biased mutational spectrum and increased homeologous recombination).

Transition mutations dominated the mutational spectrum.> -wrap-foot> One straightforward pattern noted in the earlier study was continued.

The p. Arg555Trp mutation of the TGFBI gene was associated with TBCD, which revealed a novel phenotype-genotype correlation within the mutational spectrum of phenotypically diverse corneal dystrophies.

A prime example of a mutational spectrum shift in mutators is the 230-fold increase in indel rate that was localized to within homopolymeric tracts.

The mutational spectrum of these mutations has recently been described (Lee et al. 2012).

To explore the mutational spectrum for diverse mutator alleles in a whole-genome context we devised a mutation accumulation experiment.