Sentence examples for mutational spectrum in from inspiring English sources

This is in stark contrast to the mutational spectrum in probably all other dumpy exons where the mutations are almost exclusively deletions or nonsense mutations.

The analysis of duplication-inferred mutations (DIMs) was restricted to intergenic regions of duplications, focusing on the mutational spectrum in regions that are believed to be more neutral with respect to selection forces.

It will be of great interest to synergize miRNA profiles with the genomic and epigenomic mutational spectrum in HNC for the identification of novel specific therapeutic targets.

Taken together, incorporation of tissue driven molecular analysis of the sub-type specific drivers and mutational spectrum in HNC and EMT offers great translational potential.

This simple approach is thus powerful for detection of a mutational spectrum in recent mammalian evolution.

Currently, it is not known why there is a different mutational spectrum in those cancer types.

Current estimates of the mutation rate and the mutational spectra in mismatch repair defective cells are primarily limited to a small number of individual reporter loci.

In fact, even in the one case (unclustered bottom strand mutations, Figure 5B) where we detected mutational spectra in addition to that generated by the TpC-specific deaminases, the spectra induced by T/G and U/G repair were very similar.

Our data suggest that mutation rate, the pattern of copy number variations, and the mutational spectra in the BP-NET cell lines are more similar to the changes observed in small cell lung cancer than those found in primary BP-NET.

Consistent with this antecedent, we observed similar mutational spectra in the mucA, lasR and mexZ genes of hypermutator and nonmutator isolates.

The mutational spectra in the genealogies of these two classes of haplotypes are therefore sharply different (Figure 3 and Figure S4).