Sentence examples for mutational silencing of from inspiring English sources
It is possible that either through abrogation of the effect of E7 or as a result of epigenetic or mutational silencing of host p16 (O'Regan et al, 2008), the HPV+ve/p16−ve tumours lack the molecular consequences of E7 expression and that one of the consequences of this is lower radiosensitivity compared with HPV+ve/p16+ve tumours.
Alternately, absence of EST support might be indicative of mutational gene silencing, which is one of several possible evolutionary fates of duplicated genes [ 26].
Genetic screening of cell lines did not reveal any mutational alterations in the SIP1 gene, suggesting the implication of epigenetic regulatory mechanisms for the silencing of SIP1 in HCC.
The role of aberrant methylation in CLL was highlighted by the finding of preferential promoter methylation-directed gene silencing of ZAP-70 and TWIST2 in subgroups of CLL defined by IgVH mutational status (Corcoran et al., 2005, Raval et al., 2005).
However, non-mutational functional suppression of BRCA1/2 could result from various mechanisms, such as hypermethylation of the BRCA1 promoter or silencing of BRCA2 by other proteins [ 19, 20].
One is the temporary silencing of Alberta.
More silence of the lambs?
Or the silence of the Old World?
The Silence of the Lambs (1991) 12.
But it was a silence of serenity, a warm, human, silence, a silence that inspired.
