Sentence examples for mutational roles of from inspiring English sources

The rationale for this approach is that the presence of distributional anomalies in IR numbers or features might suggest or support proposed functional or mutational roles of genomic IRs.

Our mutational analysis highlights the roles of PEHE and Cter.

Systematic mutational analysis revealed distinguishable roles of two phosphorylation sites, Thr696 and Thr853, in the regulation of MLCP.

To help clarify the roles of mutational biases and selection on the GC content of the Hodgkinia genome, we sought to determine the direction of Hodgkinia's mutational bias (if any) from existing population data generated during genome sequencing.

Single gene mutational analyses can identify the roles of individual genes within cellular pathways, whereas systems genetic approaches that exploit natural variation can construct genetic networks that underlie phenotypic variation.

Mutational analysis demonstrated the important roles of several active site residues, namely, Tyr55, Tyr114, and Arg351).

In the present study, we performed a systematic mutational analysis to uncover the roles of highly conserved amino acids and establish whether "domains" with distinguishable functional roles might indeed be present.

Because IHC analysis is more practical for application in the clinic than mutational analysis, the role of p53 accumulation should be analyzed in ER-positive breast cancer by treatment.

In this work, we use a series of biophysical and cell-based approaches, together with mutational analysis, to distinguish between the roles of ATP binding and ATP hydrolysis in RIG-I function.

This mutational hotspot is explained by the multiple roles of the TED domain.

The structural investigations and mutational analyses allowed us to gain insights into the roles of individual residues.