Sentence examples for mutational robustness in from inspiring English sources
For example, genetic complementation decreases the mutational robustness of viruses [ 9], while high mutation rates favor mutational robustness in simulated digital organisms [ 10].
Differences between these strains may be the result of a greater natural mutation rate and/or reduced mutational robustness in the CB4856 strain relative to N2.
Keller, P. J. and Knop, M. Evolution of mutational robustness in the yeast genome: a link to essential genes and meiotic recombination hotspots.
Here we describe the development of Allosteric RNA Designer (ARDesigner), a user-friendly and freely available web-based system for allosteric RNA design that incorporates mutational robustness in the design process.
Mutational robustness in evolution could be described by a trade-off between two features of the robustness to network topology and parameters.
An alternative hypothesis, direct selection, argues that selection can act directly on both mutational and environmental robustness, and that selection has been strong enough to have an observable effect on mutational robustness in particular [10], [13], [16].
The latter data seem to emphasize the connection between the structure of the code and its robustness to errors of translation as opposed to mutational robustness because, in the latter case, there would be no difference between the effects of mutations in the three positions of the codon.
This explains why the increase in mutational robustness is not observed in most cases, and why, for the cases in which flatter solutions evolve, they are most often outcompeted by quasispecies with a highly structured mutational neighborhood.
Perhaps selection for mutational robustness was stronger in the 5' UTR than in the coding sequence because it has to ensure the recruitment of the host translational machinery.
Also, the analysis of gene expression noise in yeast suggests that noise control may indirectly increase mutational robustness, which might in turn hamper evolvability at the level of gene expression [ 19].
The resulting distribution of R μ, along with the E. coli mutational robustness is displayed in Figure 4d.
