Sentence examples for mutational profile in from inspiring English sources

Among CRCs with a PIK3CA mutation, 77% showed concurrent mutations in other cancer-associated genes, and 4% of CRC did not neatly fit into either the chromosomal instability pathway or CpG island methylator phenotype/microsatellite instability pathway, suggesting overlapping mutational profile in some tumors.

It will be important to learn more about the function of this gene and its potential mutational profile in breast cancer.

Because variations in the frequency of EGFR-activating mutations in East Asians and other patients with lung cancer have been described, we evaluated the EGFR mutational profile in tumour samples from European patients with TNBC.

In contrast, when the mutational profile in follow up biopsies differs from that of the initial biopsy, new clones of cells, as identified by different mutations, have likely evolved.

Thus, in contrast to the mutational signatures found in nuclear genomes, where there is striking heterogeneity both across tumor types and across individuals within a tumor type (Alexandrov et al., 2013), the mutational profile in the mitochondrial genome of somatic cells is remarkably homogeneous.

Bolli, N. et al. Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.

Sequencing of 87 genes presented similar mutational profiles in Korean MDS patients compared with previous reports.

Bolli N, Avet-Loiseau H, Wedge DC, Van Loo P, Alexandrov LB, Martincorena I, et al. Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.

Our data on 8- to 11-mer microsatellites was concluded to represent mutational profiles in the quasi-exponential stage.

Molecular epidemiology studies have associated mutational profiles in these genes with specific exposures.

Our study has limitations, including a small sample size that limits our ability to calculate the diagnostic performance of mutational profiling in pancreatic masses and associated biliary strictures.