Your English writing platform
Discover LudwigSuggestions(5)
Exact(1)
We also compared outcomes of cases with complex mutational phenotypes for prognostic/predictive utility.
Similar(59)
We identified ~200 orthologous mouse genes in the database, which we analysed for site of expression and mutational phenotypes.
An alternative way to investigate possible pleiotropic effects is to examine mutational phenotypes.
In particular, 18 of the 58 genes were associated with mutational phenotypes shared mainly between humans and dogs (Table 2).
We observed consistent phenotypes for each MO.
Find the phenotypes for each potential offspring.
The mutator phenotype is suppressed by the resulting mutational load only under extreme parameters: where deleterious mutations are common, the cost of deleterious mutations is prohibitively high, and the benefit for driver mutations is extremely low.
We conclude that hypermethylation of MLH1, when occurs in an adenoma cell with BRAF oncogenic mutational activation, drives the pathway for MSI cancer by providing the cells with a mutator phenotype.
Indeed, numerous studies have exploited mutational compensation for defective phenotypes as a way of obtaining insight into the genetic and phenotypic bases of traits.
The very idea of a mutational writing phenotype as articulated here is new.
Author response: The theoretical and empirical exploration of the mechanisms of the mutational writing phenotype will be exceptionally exciting.
More suggestions(1)
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com