Sentence examples for mutational patterns of from inspiring English sources
The scoring system is based on possible mutational patterns of the sequences.
There is a controversy about BRAF and RAS mutational patterns of FVPTC according to its histologic subtypes [ 16, 27].
In this study, we characterized the mutational patterns of nine fungal genome sequences to determine whether the signatures of RIP activity are present.
They revealed the characteristic mutational patterns of UV light and tobacco carcinogens respectively (see above) and provided strong evidence for the past activity of TCR.
We previously reported differences in mutational patterns of the p53 gene in primary breast cancers from Midwest US Caucasian, African-American and Austrian women.
These methods were used to analyze the mutational patterns of TE-like repeat sequences from the genomes of fungal species from each major subphylum within the basidiomycete fungi (table 1).
In glioblastoma multiforme, it was demonstrated that treatment with an alkylating agent, such as temozolomide, significantly elevates the numbers of somatic mutations and results in a distinct mutational pattern of C > T transitions [ 41].
This proportion, as well as the spectrum of mutated codons in the gene (the hotspots), reflect the p53 mutational pattern of other tumors.
Our results showed that BRAF and NRAS mutations were detected in 47% and 33% of nodular melanoma, respectively, and that there is a discrepancy in mutational pattern of tumoral sample because in the 36% of patients a different mutation, in at least 1 area of the tumor, was found by LCM analysis, giving evidence of the presence of different clonal cells populations.
To determine whether the mutational pattern of BIGH3-linked corneal dystrophies (CDs) can accurately predict the clinical course of the disease and be helpful in planning adequate surgical treatment.
We analysed the mutational pattern of all kinases quantified in our Kinobead assay and could correlate a subset of these mutations with a differential response of the kinases to Hsp90 inhibition.
