Sentence examples for mutational pattern in from inspiring English sources

23, 24 K- ras gene mutation, which is another important mutational pattern in NSCLC, also was found not to be correlated with either Axl or Gas6 expression level.

Kress, S., C. Sutter, P. T. Strickland, H. Mukthar, J. Schweizer, and M. Schwartz (1992) Carcinogen-specific mutational pattern in p53 gene in ultraviolet B radiation-induced squamous cell carcinomas of mouse skin, Cancer Res.

We did not find any particular mutational pattern in the H5 patients (compared to controls) except for a threefold increase of the H5 subgroup (H5a) characterized by a transition at position 4336 (tRNAGln gene) that has been previously shown to be associated with AD [24], [25], and a sevenfold increase of the synonymous mutation at np 15833 which defines the H5a1 sub-haplogroup.

Thus, no immediate assumption can be made concerning specific phenotypes conferred by the related mutational pattern in those 173 genes between E/F and invasive strains.

We sought to investigate whether exposure to wood dust was associated with a specific mutational pattern in the K- ras gene in a large, representative study population.

The binding pattern of acrolein−DNA adducts is similar to the p53 mutational pattern in human lung cancer, implicating acrolein as a possible major cigarette-related lung carcinogen (27).

However, the influence of specific mutations on mutational patterns in the genome is usually not well characterized.

Transcription introduces several biases in mutational patterns; in particular it invokes strand specific mutations.

In this study as in the others [ 10, 11], transversions at guanine (G to T) were the most common events (46% of all mutations), attesting to the role of tobacco carcinogens in shaping the mutational patterns in this tumor.

From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes.

Chan-On, W. et al. Exome sequencing identifies distinct mutational patterns in liver fluke related and non-infection related bile duct canon-infection related