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Mutational modification in gene regulation networks alters gene expression dynamics that provide a basis for morphogenetic diversity.
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Chemical or mutational modification of the zinc-coordinating ligands in isoleucyl-tRNA synthetase (of E. coli and Thermus thermophlilus) affects the enzyme efficiency [ 5, 6].
The GPI-anchored CEACAMs, which have been identified so far only within primate CEA families, were generated by mutational modification of a transmembrane domain exon in a CEACAM1-like ancestor [ 8].
The continuing mutational modification of H1N2 and H3N2 have resulted in entropy patterns distinctive of the human transmitted influenza A viruses with a large number of amino acid sequence patterns that differ from those of the avian to avian counterpart.
Considerations of mutational modifications demonstrate how a GATA3 positive cancer may actually produce a distinct clinical phenotype.
The lack of further modifications in the BRAF mutational condition, once melanoma has metastasized, can possibly result from absent/limited intratumor heterogeneity for the mutation in the metastatic disease.
Consider these modifications in turn.
Does BAIBA produce similar modifications in humans?
Modifications in the sessions are required.
Histone modifications in chromatin regulate gene expression.
We discuss additional aspects of IDP evolvability and mutational tolerance in the section on post-translational IDP modifications (see section 3.6).
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