Sentence examples for mutational frequency and from inspiring English sources

Mutational frequency and type of somatic point mutations were highly variable among the different MPNSTs modeled, but very consistent when comparing primary tumors with matched orthoxenografts generated.

We used statistical analysis of sequence data generated by the Cancer Genome Atlas initiative including somatic mutation load (SML) analysis, Kaplan Meier survival curves, gene mutational frequency, and mutational enrichment evaluation to study the genomic landscape of breast cancer.

We used rodent transgenic cell lines containing 50 70 copies of a LacI transgene to provide the enhanced sensitivity required to quantify mutational frequency and type in the 1100-bp LacI target as well as assessment of DNA damage to the entire 45-kbp construct.

On the molecular level, TCZ therapy reduces the mutational frequency and RGYW hotspot targeting in all DN B cells over a period of 1 year.

The focus of this investigation was to measure the mutational frequency and dynamics both in vitro and in vivo of the SARS-CoV.

At present the literature contains little information regarding ER-α gene expression, mutational frequency, and allelic variants in breast cancer among Asians, especially those who reside in their native country.

To address this, we identified two cohorts of patients across several institutions that were profiled for more than four clinically significant genes as shown in Figure 5. Encouragingly as expected, mutational frequencies and mutual exclusivities in signaling mutations in these representative subgroups were similar to those reported from other published cohorts.

As we hypothesized, the mutational frequencies and rates of TGFBR2 exon 3 and ACVR2 exon 10 microsatellites are dependent on the MMR deficient background with hMLH1−/−>hMSH6−/−>hMSH3−/−.

Thus, we sought to determine and compare the mutational frequencies and spectra in NSCLC and breast carcinomas.

It is known that there are significant differences in the mutational frequencies and spectra in lung cancers between smokers and nonsmokers.

Although the corresponding VH repertoire was similar in the blood and in the parotid, this analysis detected glandular accumulation of memory B cells with significantly enhanced mutational frequencies and shorter third HCDRs than their counterparts in peripheral blood [ 24, 79].