Sentence examples for mutational frequencies of from inspiring English sources
There were no compound heterozygous mutations or homozygous mutations in any of these cases, and the mutational frequencies of codons 12, 13, 61, and 146 were 25.4%, 9.2%, 0.4% and 1.3%, respectively.
Morin et al. were the first to report on somatic EZH2 mutations involving exon 15 (EZH2Y641F/N/H/S), with mutational frequencies of ∼22% in germinal center B-cell diffuse large B-cell lymphomas and 7% in follicular lymphomas.
However, it should be noted that the mutational frequencies of CD27- B-cell-derived mutated IgVH rearrangements in pSS were significantly lower than that of their CD27+ memory B-cell-derived counterparts [ 24, 25].
The largest study of IDH mutation analysis in MPN involved 1473 patients and reported IDH mutational frequencies of ∼2% in PV, 1% in ET, 4% in PMF and 22% in blast-phase MPN.
The dynamics of the functionality of QS systems in the clinical strains were correlated to rhamnolipids and elastase production as well as to the mutational frequencies of the isolates.
The four extracellular SCR domains showed similar mutational frequencies of 15 non-intronic mutations/100 residues.
For example, determining mutation prevalence (for a range of specific mutations, as well as mutational frequency of any single gene), or the frequency at which any particular gene leads to any single phenotype, remains to be defined for most diseases.
Several specific residues for frequent mutations were found and the mutational frequency of reductase domains was much higher than that of heme domains.
Similar to glioma, IDH1 and IDH2 mutations are mutually exclusive, though the mutational frequency of IDH in AML is much lower (23%) (Chou et al., 2011b; Ward et al., 2010).
In endometrial and colorectal tumours, a set of ultra-hypermutators with increased mutational frequency of transversions was associated with somatic mutations in polymerase ɛ [ 44,72].
Mutational frequency of Ig-R did not change in DN B cells during adalimumab therapy.
