Sentence examples for mutational deletion of from inspiring English sources

Mutational deletion of HA glycosylation sites can affect viral receptor binding [30].

The probability of an independent mutational deletion of seven residues from a C+ gene leading to the exact same indel pattern as in the pre-existing C- IV) gene is low.

Over 1900 disease-causing CF mutations have been identified, and it has been estimated that approximately 70% of CF chromosomes worldwide contain at least one copy of the mutational deletion of phenylalanine at residue 508 (ΔF508) in the CFTR protein, which is categorized as a Class II defect (http://www.genet.sickkids.on.ca/cftr).on.ca/cftr

To illustrate application of the run through stop mutagenesis and DNA splicing technique, we have carried out splicing of two segments of the human cofilin 1 gene and introduced a mutational deletion into the product.

Therefore, throughout the genome, the mutational deletion bias is largely compensated by stronger selection against deletions.

The two-hit model of rAML involves a first irreversible mutational hit (interstitial deletion of one Sfpi1 gene on chromosome 2) creating intermediate cells that have a growth advantage but which are not fully malignant.

Afterwards, using different experimental techniques (RT-PCR of intermediate splicing products; RT-PCR test for lariat structures of intermediate introns; and mutational and deletion analyses of RP-sites) Burnette et al. [13] characterized in detail a mechanism that subdivides large introns by recursive splicing at non-exonic elements and alternative exons.

EMSA (Electrophoretic Mobility Shift Assay) showed that both regions have RNA-binding activity whereas that mutational analysis reported that either deletion of any of these regions, or loss of the basic amino acids, interfered with the viral intercellular movement.

Mutational analysis has shown that deletion of either Qox or Qxt has no effect on aerobic growth rate [ 56], which is in agreement with the predictions of iRsp1095.

Although no specific function was assigned to the exon 5 domain by mutational and deletion analysis of the mouse and human protein counterparts [44,45], our cell culture data indicate that the peptide sequence encoded by exon 5 contributes to the transcriptional activity of Mef2ca.

Mutational analysis of the MC2R revealed a homozygous deletion of a cytosine (C) nucleotide, resulting in a frameshift at amino acid position 235 and premature stop codon.