Sentence examples for mutational consequences of from inspiring English sources

A second hypothesis is that the RNA-editing mechanism may evolve as a way to ameliorate the mutational consequences of asexuality in asexual organellar genomes (Lynch 1997; Lynch et al. 2006).

It can be predicted that the mutational consequences on channel function strongly depend on the firing pattern of neurons.

The chemistry and biology of electrophile−DNA reactions have been extensively studied, providing in many cases a detailed understanding of the relation between adduct structure and mutational consequences.

The presence of TEs (as dispersed, mobile, and repeated elements) has two major mutational consequences at the DNA level: insertion within a locus, and ectopic recombination leading to different types of rearrangements.

There is a striking difference in predicted mutational consequence leading to cataract or syndrome.

This mutational genetic variance both depends on the mutation rate and on the phenotypic consequences of the mutations (the mutational effects).

We present here a comprehensive genome-wide analysis of the prevalence, mutational spectrum, and functional consequences of microsatellite instability (MSI) in cancer genomes.

The above study reveals how purifying selection contrasts "accelerated" mutational meltdown, preventing the consequences of Muller's Ratchet in mammalian mtDNA.

The ready availability of genomic sequence information along with an extensive body of knowledge about gene function in this species provides an exceptional opportunity to examine the consequences of mutational change on the composition of the genome.

Specifically, we address a facet of the mutational repertoire of cancers, that has not received mathematical attention, i.e. the immunological consequences of the mutational burden of tumors.

Our findings pave the way for detailed mutational analysis of the functional consequences of post-translational modification of Polycomb proteins.