Sentence examples for mutational characteristics of from inspiring English sources
However, it is acknowledged that one of the limitations of the present study was that the gene mutation was not analysed and so the mutational characteristics of the duodenal GISTs were not known.
We examined whether the well-known mutational characteristics of the human genome may create the observed deficit of some short sequence motifs.
In summary, our results suggest that the collection of human and other mammalian nullomers are likely a by-product of the mutational characteristics of the genome, with hypermutable CpG dinucleotides playing a major role.
Instead, they proposed that the mutational characteristics of the genome, namely the hypermutability (hence deficit) of CpGs in vertebrates, provides a reasonable explanation for the multiple CpGs observed in all of the shortest absent words in the human and other mammalian genomes [4].
To reveal mutational characteristics of NSBs, we sequenced the genome of A. oryzae RIB326 and compared it with strain RIB40.
Several analogues of FST have been developed to account for the mutational characteristics of microsatellites (Slatkin 1995; Michalakis and Excoffier 1996; Hedrick 2005; Jost 2008).
Our work provides a detailed overview of the mutational characteristics in each of nine major cancers and highlights that the mutational signature profile is representative of each cancer.
Nonetheless the complex interaction of these markers with many other gene mutations that can modify the final prognostic impact, or the effect of intrinsic mutational characteristics, such as, allelic burden or mutation site on protein function and prognosis, make molecular risk stratification a highly complex process.
Therefore, mutational characteristics, rather than selection pressures, lead to the rare occurrence and absence of certain motifs.
Available clinical and relevant mutational characteristics are detailed in Table S1.
In cancers associated with exogenous mutagens, such as tobacco-associated lung cancer and ultraviolet light-associated melanomas, we found no evidence of the mutational signatures characteristic of these carcinogens among the mtDNA mutations.
