Sentence examples for mutational behavior of from inspiring English sources

Finally, despite having found general tendencies regarding the statistical mutational behavior of the regulatory networks, no systematic relationship was observed between increasing network complexity and the epistatic nature of the regulatory networks.

XDET compares the mutational behavior of a residue position with the mutational behaviors of the entire alignment, which assumes the positions showing a family-dependent conservation pattern will have similar mutational behaviors as the rest of the family [38], [42].

In this study, we focus on the mutational behavior of dinucleotide microsatellites.

Genome-wide studies have identified directional biases in the mutational behavior of long microsatellites.

Our work combines computational and experimental approaches to explain the complex mutational behavior of dinucleotide microsatellites in humans.

Importantly, our results uncovered a conspicuous, biphasic mutational behavior of repetitive loci that depends on repeat number.

This suggests that loci above nine repeats exhibit the dynamic mutational behavior characteristic of microsatellites (hyper- or microsatellite mutability).

A defining characteristic of microsatellites is their dynamic mutational behavior and high level of germline polymorphism among individuals (Ellegren 2004).

We observed that indeed polymorphism prevalence grows with repeat number (figs. 1 and 2)—however, it does so with qualitatively different regimes, suggestive of two distinct modes of mutational behavior.

Our study used various experimental approaches to examine the mutational mechanisms operating within mature microsatellites, which we define as alleles that are not expected to mutate to lengths below or at the threshold for microsatellite mutational behavior in one round of replication.

We observed two distinct modes of mutational behavior.