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Transposon mutagenesis has also provided an alternate mutational approach in Z. mobilis.
Based on a bioinformatic and mutational approach in yeast Liu and co-workers [ 30] suggested the co-evolution of Mbf1 with Tbp in Eukaryotes and Archaea.
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We focus on the mutational approach to differential equations in metric spaces by Aubin [9, 10, 11].
Site-specific assignment of these methyl groups can be made using a mutational approach.[ 5a, 18] In addition, the "singly labeled" LSm1 7 rings significantly resolved the spectral overlap of the spectrum.
An in vivo mutational approach for yMbf1 revealed that combinations that occur naturally (e.g. the mutant yMbf1-D112R (WT-Tbp-68Q); Archaea) showed no effect, whereas combinations not normally found, like yMbf1-D112K (WT-Tbp-68Q), were sensitive to 3-AT, indicating that the interactions between yMbf1 and yTbp were disrupted in the latter mutants [ 30].
Our mutational approach to improve the psd module resulted not only in variants with decreased stability, but these variants showed a higher dark/light switching ratio as well.
6a To validate and complete the Rrp42 assignments in the exosome complexes, we took a mutational approach 6c, 13.
The results show the feasibility and potential versatility of mutational approach for the development of the highly-sensitive microbial biosensors.
We decided to undertake a mutational approach to characterize the subunit interfaces that form the protofilament.
Therefore, any standard random mutational approach to analyze DNMT1 function would be extremely laborious.
Here, we apply an unbiased mutational approach to this problem.
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