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Such a phenomenon may lead to mutational aberrations in the recipient cells and enhance the probability of wound carcinogenesis.
Mutational aberrations in PIK3CA and PTEN and highly expressed baseline pS6 (serine 235/236 and 240/244) seem to be significant and reliable biomarkers for predicting the treatment response of everolimus.
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It is our hope that some of these putative chromosomal interactions might correlate with interesting phenotypes, related to such diverse topics as cytogenetic aberrations in tumours, mutational and recombinational hotspots, and disease-related chromosomal regions.
We examined RAS mutational status and correlated this with presenting morphology, cytogenetics, clinical outcome and other gene aberrations in a large cohort of Chinese acute myeloid leukemia (AML) patients.
Overall, our results illustrate the confluence of multiple genetic aberrations in HCC, where inherited and de novo retrotransposition events form part of a wider mutational landscape.
This can cause unexpected aberrations in research findings.
The teeth show aberrations in number, size and morphology.
This subtype is characterized by aberrations in MITF.
Fusion genes are common aberrations in cancer.
Specifically, the review summarizes genomic aberrations in mOGCTs as studied by ploidy, cytogenetic banding, comparative genomic hybridization (CGH) and microsatellite loci analysis, and genome-wide mRNA expression and microRNA (miRNA) expression studies as well as expression of single genes and proteins, including relevant mutational studies.
Pesticides which cause chromosome aberrations in plant cells also produce chromosome aberrations in cultured animal cells.
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