Sentence examples for mutation with high from inspiring English sources

For many pairs we found at least one mutation with high VAF in both samples suggesting a common founding clone.

For all three diseases, delivering the appropriate Cas9 and guide RNA corrected the mutation with high efficiency.

The EGFR-DMP assay was able to rapidly detect the mutation, with high sensitivity and specificity.

These data suggest that both our CRISPR/Cas9 vectors can effectively induce mutation with high frequency (near 100%) in regenerated T0 plants in tomato.

This study provides a new allelic discrimination method that detects the MDR1 mutation with high specificity and reliability and is useful for routine diagnostics.

A mutation with high frequency in the Ashkenazi Jewish population is N370S.

Also, the mean length of the haplotypes decreased, which localizes the mutation with higher precision.

Indeed, multiple neutral changes along the mutational landscape of a protein may precede mutations with high advantageous fitness effect [ 27].

We used Cas9 mRNA as opposed to CAS9 protein, as this approach has been shown to generate on-target mutations with high efficiency2.

The use of hrMCA in combination with SAG from genomic DNA enables rapid detection of COL3A1 mutations with high efficiency and specificity.

Recently, heavy-ion beams have been used widely to generate mutants of higher plants, because, in contrast to other mutagenic techniques, they induce mutations with high frequency at a relatively low dose, and various phenotypes may be obtained without other plant characteristics being affected9,10,11.