Sentence examples for mutation will require from inspiring English sources

The possible mechanism of this mutation will require further investigation.

Because of the multitude of other candidates in this region, the identification of the causative mutation will require narrowing the region of linkage.

To fully elucidate the pathogenic mechanisms for any specific mutation will require the integration of analyses across multiple levels, from protein function to systems neuroscience.

40 The clinical relevance of integrase mutations will require longer-term follow-up.

Whether there was a relationship between drug resistance and these mutations will require further study.

Such mutations will require experimental evaluation through site-directed mutagenesis and spectrophotometric analysis of expressed visual pigments [ 45].

However, this phenotype was reported to be sporadic and a careful comparison of the phenotypes from the different mutations will require matching their genetic backgrounds.

Hence, the overall direction of epistasis for fitness, and the possible role of compensatory mutations in pushing toward net antagonistic epistasis among random mutations, will require more study in higher organisms.

Complex multifactorial diseases, which may depend on human-specific variants with small effect size or more specific molecular effects such as gain-of-function mutations, will require more customized approaches such as knockin of specific human mutations.

In contrast, rescue of the p.T158M and p.R306C point mutations will require targeted correction of the expressing allele, or transgenes that simultaneously knockdown the hypomorphic mutant MECP2 and express WT MECP2 at normal levels.

17– 19 To effectively study targeted agents against such low-frequency mutations will require close cooperation between academia, industry, and regulatory groups on a global basis because of the rarity of patients harboring these oncogenes.