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Thus, the A41D mutation will abolish AcrR's repressive activity.
The E406A mutation will abolish this hydrogen bond and thus presumably allow the side chain of Gln453 to rotate.
Similar(58)
Clearly, both the R402H and the R402C mutations will abolish the cation π interaction, since neither histidine nor cysteine can be involved in this type of interaction.
We speculate that mutation of this residue will abolish or weaken the electrostatic repulsion, which will allow the ion to permeate along the side wall opposite to D and E given the spacious SF vestibule of eukaryotic NaV channels and thus will impair the Na+/K+ selectivity.
DOI: http://dx.doi.org/10.7554/eLife.06179.009 If heterochromatin spreading is the cause of the initial growth defects of mst2∆ epe1∆ cells, we expect that mutations blocking heterochromatin spreading will abolish such an effect.
It will abolish the House of Lords, but quite probably will not abolish the Monarchy.
So we will abolish the death tax.
We will abolish the national curriculum.
Or otherwise it will abolish itself".
The next Labour government will abolish the non-dom rule".
When I am elected President, I will abolish international calling.
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