Sentence examples for mutation widening the from inspiring English sources
The cysteine mutation widening the lumen of the 6-bladed β-propeller (β6) domain enhanced catalytic activity, which was restored to normal values after its alkylation.
The modest distortion suggested that the FARS2 mutation would widen the ATP binding pocket and thus decrease affinity for ATP (Fig. S1).
The locations of beneficial mutations in AcrB suggest their contributions in widening the substrate channel, altering the dynamics of substrate efflux and promoting the assembly of AcrB with the outer membrane channel protein TolC for more efficient substrate export.
"Widening the gates would strengthen the walls".
This widening project included widening the bridge over the Pennsylvania Railroad in Farnhurst.
They are widening the circle.
Increase the field of view by widening the sector width.
Keep widening the sides of the opening.
These observations support the idea that mutation to smaller residues widens the cavity to allow for the binding of an extended isoprenoid tail, while mutation to bulkier residues hinders this ability.
This means that while SITS narrows the distribution of mutations by letting the less damaged cells live longer and removing highly mutated cells, the T-SCE widens the distribution of mutations as it both widens the distribution of cell longevities and at the same time recombination makes cells "forget" about their history of exposure to DNA damage.
