Sentence examples for mutation which will from inspiring English sources

We then studied strain phenotypic diversity generated by mutation, which will lead to antigenic differences in a pathogen, such as the influenza A virus, and incorporated those in an SIR model with reinfection.

Therefore, the same dataset originating from a single WGS run for a given mutant will not only reveal the SNP distribution but will also greatly improve the ability to identify the phenotype-causing mutation, which will be one of the few -if not the only- variants in an interval defined by the SNP mapping.

It will be interesting to investigate the molecular nature of the Caf1p55 long mutation, which will likely provide clues regarding how Psc overexpresion affects CAF1p55 activity.

This finding expands the mutation spectrum of SMAD3 gene and highlights the importance of screening patients with aneurysms as well as early onset osteoarthritis for SMAD3 mutation, which will facilitate identification of at-risk family members and early intervention.

Additional studies using population-based case control and/or familial samples will be useful to define the penetrance of this mutation, which will have important clinical implications for families that carry the G84E mutation.

This introgression will provide a more uniform genetic background at most loci that are not linked to the mutation, which will help during initial mapping because marker polymorphisms will be known for the inbred.

For example, treatment of B-Raf mutated melanoma selects cells with Ras mutations which will short-circuit the inhibition and re-establish the activation of MAP kinases in the tumor and also in normal cells, thus generating new skin carcinoma [ 142].

CAS, which couples modern digital imaging technology with a longitudinal temporal design, can be applied to identify a large number of motility mutations which will provide a research resource for workers in the fields of neuromuscular functioning and development in both normal and disease states.

Genetic mutations, which will lead to the reduction of hemoglobin β chain (β-globin) and erythrocytes, finally cause oxygen shortage, bone deformity, organ dysfunction and even organ failure in many parts of the human body (Cao and Galanello, 2010).

Such a mechanism of interaction will make interface V more tolerant to mutations than protein-protein interaction mediated by rigid structures, as long as the mutations, which will occur simultaneously on both sides of the interface, permit the co-folding of the modified AA loopp.

Somatic single-base substitution mutations like the ones found in human tumors in KRAS codons 12 and 13 correspond to SNPs for the cells bearing these mutations, which will appear as heterozygous by any testing (1∶1 ratio for the mutant vs wild-type alleles in mutant cells).