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We found that two-fifths of colorectal cancer patients in Taiwan have a p53 mutation, which could be used as a marker of colorectal cancer.
The clear 10.9-kb band detected on a Southern blot assay for fragile X syndrome mimics a large, methylated full mutation, which could result in a misdiagnosis without the benefit of family studies and further testing.
You also inform her of the chance that she might be a carrier of a DNA mutation which could be further analysed by a clinical geneticist.
Asking Prof. Milani how people usually accept 'the bad news' that their genome may carry a mutation which could be, for example, in the high-risk zone of breast cancer, she said that people get informed by health experts giving them counseling and the privilege of choice to manage the risk.
With most viral infections, we should always be wary of viral mutation, which could potentially thwart our attempts at "functional cures".
However, unlike the study conducted in 1999, only 16% of the isolates have the BR and the 164L mutation which could be due to the loss of the selective pressure when SP was removed from the health clinics (Bacon et al, data not shown).
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Stanford Bio-X affiliated faculty Gill Bejerano and Stanford Bio-X Fellow Johannes Birgmeier used cryptography to cloak irrelevant information in individuals' genomes but reveal disease-associated mutations, which could improve patient privacy.
Screening cells: New research reveals that induced pluripotent stem cells (shown here) carry a number of genetic mutations, which could have implications for their therapeutic use.
Such information may result in the design of highly specific agents that target specific mutations, which could result in more efficacious treatments.
We find good agreement with the currently known experimental data and we predict a number of new mutations which could be used to validate further our predicted structures.
Since PTPRS was reported to have a tumor suppressor-like role24,25,26, we postulated that the somatic mutations of PTPRS, if functional, might be inactivating mutations, which could mediate RAS/ERK pathway activation, which is a driver of tumorigenesis3,4,5,6.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com