Sentence examples for mutation which arises from inspiring English sources

The resulting increase or decrease of physical genome redundancy may, nevertheless, determine the functional effect of a secondary mutation which arises later during tumor evolution and which targets an additional copy of the gene or regulatory element.

Mice affected by a spontaneous mutation which arose within our colony exhibited a neuromuscular phenotype involving tremor and characteristic stretching of the rear limbs.

Distance measurements of the A70T mutation, which arose in the first round of error-prone PCR (Dieselzyme 2), shows that the hydroxyl from the threonine forms a new H-bond interaction with T68 and the backbone carbonyl of K72.

This diversity reaffirms the heterogeneity seen in the phenotype genotype relationship of mt-tRNA mutations, which arises due to the complex interactions between nuclear and mitochondrial genetics, the dramatic variations in tissue segregation of heteroplasmic mt-tRNA point mutations, and the threshold effect for pathogenicity.

Natural selection and genetic drift require genetic variation, which arises from mutation and gene flow     4.

Evolution, defined as the change in genetic makeup of a population over successive generations, requires genetic variation, which arises from mutation and recombination.

(3) Natural selection and genetic drift require genetic variation, which arises originally from mutation and can be augmented by subsequent gene flow.

The second finding is de novo point mutations, which arise spontaneously in the sperm of adult men.

Amplification of the rrnB-rrnE region adds targets for purO mutations, which arise within the amplified purHD operon.

Mutations resulting in genomic instability induce lineage selection effects as stochastic mutations which arise in genetically unstable CCLs are non-random with regards to mutation probability and mutation patterns.

We first describe the invasion properties of the beneficial mutation A1, which arises in linkage to a migration selection polymorphism at the background locus B. Because we assume that the island population is large, random genetic drift is ignored after A1 has overcome the initial phase during which stochastic loss is likely.