Sentence examples for mutation which are from inspiring English sources

Intriguingly, they also reflect the relatively narrow spectrum of tumor types exhibiting high rates of ATRX mutation, which are notably enriched for neuroepithelial derivation (e.g., adult and pediatric glioma, neuroblastoma, and pancreatic neuroendocrine tumor)6.

VIGS, however, is considered to be undesirable for practical system, because there is a risk for the potential of generating new infectious viruses by recombination and mutation which are generated by errors during the replication of genomes [13].

However, formal tests for selection based on allele frequency skew require strong assumptions about demographic history and mutation, which are rarely well understood.

To minimize genetic heterogeneity, we excluded autopsy confirmed patients without TDP pathology and patients carrying a MAPT or CHMP2B mutation, which are known as non-TDP pathologies (Table 1).

However, sample ID 2 was shown to contain a c.37 G > A and a c.39 C > G mutation, which are not tested for by the TheraScreen kit and CADMA.

This is consistent with the structural effects of the present mutation, which are limited to the proximal heme site and cause the breaking of the H-bond between H160 and E210, thereby decreasing the anionic character of the latter.

All our patients were prior evaluated for the presence of the JAK2V617F mutation, which was detected in 51 cases (72%).

We do not know the clinical significance of this mutation, which is in the wing domain of NS120,21 and has not been associated with altered flaviviral fitness.

How such a mutation, which is in the transmembrane region of the M protein (with reference to the DENV M protein59), attenuated ZIKV remains to be defined.

Interestingly, SOD1-fALS patients with a G37R mutation, which is contained within segment 30KVWGSIKGL38, present longer disease durations compared to other SOD1-fALS patients25.

We extensively analyzed p.Cys282Tyr mutation which is predicted as a destabilizing and is primarily associated with the HH.