Sentence examples for mutation were necessary from inspiring English sources

A challenge for future work is to identify the other mutations that, together with the first gltA mutation, were necessary for the bacteria to evolve the ability to use citrate.

While immuno-histochemical staining for SMARCB1 protein has greatly facilitated the diagnosis of rhabdoid tumor, identification of a mutation is necessary for the ascertainment of the germ-line mutational status.

Mutation is necessary but not sufficient for phenotypic expression and there are no simple phenotype-genotype relationships.

However, some of the fish with this mutation did not have high blood glucose, indicating that the insra mutation is necessary but not sufficient to alter blood glucose regulation.

Here the effectiveness of each defense mutation is very high (going from highly susceptible to the current virus population to highly resistant), and predator adaptation is delayed because a de novo mutation is necessary to counteract defense, thus meeting both criteria predicted by our analysis.

For these, the concepts of penetrance and expressivity operate in ways which accommodate the one-one genetic determinist model where the mutation is necessary and/or sufficient for both the presence of the condition and confounding patterns of phenotypic variability.

Wild-type HSV-2 MS (ICP0+) virus was included as a control to verify that the 0ΔNLS mutation was necessary to attenuate the pathogenesis of HSV-2 infection.

However, additional studies involving older healthy family members of LRRK2 PD patients, who carry the mutation, are necessary to validate these findings.

The distance between the cut site and the mutation is necessary because of recision.

This suggests that the Crb1 rd8/rd8 mutation is necessary, but not sufficient for the development of these degenerative features.

Clearly, a first-step mutation is necessary for the development of subsequent mutations, the latter of which result in MICs that fall within the nonsusceptible category.