Sentence examples for mutation were generated from inspiring English sources

C57BL/6 mice containing the nee mutation were generated by 10 generations of successive backcrosses transferring the mutation from the originating B10.A- H2 h4 /(4R SgDvEgJ background to B6. Sh3pxd2b nee mice.

C57BL/6J (B6) mice that carry a Tipe2 gene null mutation were generated by backcrossing Tipe2 −/− 129 mice to B6 mice for 12 generations.

iPSC lines harboring the m.3243A>G mtDNA mutation were generated from patient fibroblasts with various levels of heteroplasmy.

Mice with conditional Separase inhibitory phosphosite mutation were generated, genotyped and sex determined as described [30].

Mice carrying this mutation were generated by using standard methods of host embryo microinjection of embryonic stem cells, chimera production, and germ-line transmission [54].

In order to study the functional role of the protease cleavage site, 2 alanine substitutions (either single or double mutation) were generated by site-directed mutagenesis (Figure 4B) and tested by pseudotyping lentiviral vectors with different mutants of SARS-CoV spike glycoprotein.

The hha(C18E) mutation was generated in a pET15b expression plasmid35 that produces a His6-tagged form of Hha.

The pAH79 derivative containing the gtsB(A10T) mutation was generated by amplifying the 2-kb gtsB locus using primers 22F-5324097 and 22R-5324097 from DNA isolated from an evolved clone carrying the mutation.

A mutation was generated in the site complementary to the miR-139-5p miR-139-5p miR-139-5pUTR of AMFR or NOTCH1, aseeddicated.

The RasK104R point mutation was generated by PCR-based site-directed mutagenesis of pDNR-Dual-Ras1.

The original Fmr1 knock-out mutation was generated using 129P2 stem cells [12].