Sentence examples for mutation were bred from inspiring English sources

Mice hemizygous for the hA53T mutation were bred on a mixed C57BL/6J x C3H/HeJ background to produce transgenic and non-transgenic litter mates.

Male and female mice heterozygous for the myostatin null mutation were bred in monogamous pairs and litters were weaned at 21 days of age.

What they found was that even once the mutation was bred out of a generation, the mice that had two copies of telomerase still suffered from short telomeres.

To reduce these issues, the same mutation was bred into a colony of beagles to establish Canine X-linked Muscular Dystrophy in Japan (CXMDJ) [21] which subsequently has been used to demonstrate efficacy of exon skipping therapy [22].

The floxed mice were originally bred into the C57BL/6N strain which carries the rd8 mutation, but this retinal degeneration mutation was bred out of the colony before this study was conducted.

To address whether Fbxw7 propellor tip mutant protein could promote the development of intestinal polyposis initiated by Apc mutations, R482Q mice were bred with two Apc mutants, Min 26 and 1322T.

Previously, C. elegans mutation accumulation (MA) lines were bred in order to produce populations that evolve effectively free from selective constraint [ 10].

Heterozygous " Tp53 LSL-R270H/+" [129S4(Trp53tm3Tyj)] and " Nkx3.1-Cre" [129S Nkx3-1tm3(cre Mms)] mice with prostate-specific expression of the Tp53 R270H mutation (p53 R270H/+ Nkx3.1-Cre mice) were bred onto an FVB/N background via speed congenesis to produce strain FVB.129S4 Trp53 tm3Tyj/wt); FVB.129S(Nkx3-1 tm3(cre Mms/wt) and littermate genotype negative control mice.

Fish heterozygous for the foggys30 mutation or hsp70-GFP transgene were bred to obtain homozygous embryos for analysis.

Two lines of mice expressing the mutation in Cryaa, R49CneoKI3 and R49CneoKI4, were bred.

These mice were bred to the Rb1ΔL mutation, creating a mixed 129/B6/FVB genetic background.