Exact(3)
Females heterozygous for the mutation were backcrossed for at least 9 10 generations to balb/c males to generate the KO and littermate WT mice.
Three founders for each mutation were backcrossed with C57BL/6J females.
The A vy mutation initially arose spontaneously in C3H/HeJ mice; animals carrying the mutation were backcrossed with C57BL/6J mice, followed by > 220 generations of sibling mating (Waterland and Jirtle 2003).
Similar(57)
The ju89 mutation was backcrossed multiple times.
The null mutation was backcrossed ten times onto a CD1 (ICR) genetic background.
In NOD-SCID mice, this mutation was backcrossed onto the NOD/ShiLt background.
The strain GS3347 containing sel ar584 ) mutation was backcrossed four times with N2 before deep sequencing.
The Tph1-null mutation was backcrossed on to a C57BL6/J background.
In our initial study the Perforin-2 mutation was backcrossed 7-10 times, a point that is now made clear (subsecton "Generation of Mpeg1 knockout mice").
In our initial study the Perforin-2 mutation was backcrossed 7-10 times, a point that is now made clearer (subsection "Generation of Perforin-2 knockout mice").
Each mutation was backcrossed to B6J or FeJ strains for at least 10 generations, selecting for the mutation of origin by selective PCR genotyping using primers described in the original papers (Beyer et al. 2008; Papale et al. 2009).
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