Sentence examples for mutation weakens the from inspiring English sources

Characterization of a V7F substitution in MOCS2A, identified in a patient with an unusual mild form of the disease, showed that the mutation weakens the interaction between MOCS2A and MOCS2B, whereas a MOCS2B-E168K mutatidentifiedfind in a severely affected patient attenuates binding of precursor Z.

Thus, the mutation weakens the coupling between the conformational and GTPase cycles of αβ-tubulin.

Now, Cottee et al. demonstrate that this mutation weakens the interaction between CPAP and STIL in vitro.

This mutation weakens the activated 5' splice site associated with the STOP codon and tilts the processing of the RPN12a mRNA back towards polyadenylation.

Out of three nucleotide mutations in major capsid gene, H53N mutation weakens the subunit assembly between capsomeres for the phage head; E313K reduces the fold binding between β-sheet and Spine Helix inside the peptide.

Out of three mutations in major capsid gene, H53N mutation weakens the subunit assembly between capsomeres for the phage head; E313K reduces the fold binding between β-sheet and Spine Helix inside the peptide.

A chance mutation weakening the mother-infant bond was a death sentence.

Thus the S228P mutation weakened the ability of βB1 to form heteromers with βA3, probably by perturbation of the correct refolding of βB1.

Mutations in the first (N-terminal) KOW domain did not affect the protein interaction, but the KOW1 mutation weakened the splicing activity of GPKOW.

It has been proposed that another function of chaperones is to maintain the activity of proteins destabilized by mutation, weakening the selection against suboptimal protein variants.

Turns out, some mutations made mini "super-yeasts" that were more resilient to drugs; but some mutations weakened the yeast's defenses, rendering them more susceptible to drugs.