Sentence examples for mutation we selected from inspiring English sources

Because rs12218 is a synonymous mutation, we selected two additional non-synonymous mutations (rs2229338, rs1059559) across exon 4 of the SAA1 gene for our analysis.

Second, if there is no missense mutation, we selected SNPs in 5'UTR or 3'UTR.

For each mutation we selected a sequencing primer about 50 300 bp away from the point of mutation.

For HR-mediated repair experiments such as gfp knock-in and introduction of point mutation, we selected the target sequences where it was possible to introduce a silent mutation in the PAM site.

To investigate whether AKT1(E17K) in prostate cancer was associated with a favourable clinical outcome, as suggested by the first two patients harbouring the AKT1 mutation, we selected an additional 12 paraffin-embedded primary prostate tumours.

With intent to analyze ATBF1-A mutations, we selected all the mutational spots in exon 9 and the most frequent deletion spot in exon 10 reported in prostate cancer because > 80% of the mutations reported in the paper were located in these spots (Table 2) [ 10].

Of the 563 expressed non-synonymous mutations, we selected 50 and confirmed all 50 by PCR and Sanger sequencing.

Many of the mutations we selected are likely to affect the linked processes of sugar harvesting and the control of cell growth.

To probe the characteristic pathways associated with different p53-hotspot mutations, we selected the colorectal cancer (CRC) data set in TCGA as an example.

In order to address, in vitro, the transforming potential of MLK3 missense mutations, we selected five different mutations, Y99C, A165S, P252H, R799C, P840L occurring in distinct domains of the protein.

To simulate random point mutations, we selected a genomic position uniformly at random, looked up the nucleotide at that position, and then randomly selected one of the three other possible bases at that position.