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By newly associating a weight parameter with target vector during mutation, we maintain equilibrium on the exploration and exploitation mechanism of DE.
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We maintain variation via crossover, mutation, and the creation type ramped half and half.
Therefore, as a control for the PG6 mutation, we attempted to maintain a rigid structure by replacing the same 6 residues with alanine (PA6).
Although recurrent mutation in conjunction with mutation can maintain a polymorphism indefinitely at mutation-selection balance, here Ford is clearly interested in a more active role for natural selection in the maintenance of polymorphism.
This differs from our current system where high mutation rates maintain more niches by preventing the out-competition of multiple partial solutions (the ecosystem) by the full solution.
Nevertheless the Leu1375His mutation should maintain the structural integrity of the pore helix that possibly explains the only minor functional changes.
In addition, we propose a diversity operator to be used instead of mutation and also maintain an archive of good solutions.
A mutation can increase, maintain, or decrease the diversity level of the population.
After a frameshift mutation, KalTA4 should maintain its own expression, as well as that of H2A-EGFP.
However, growing B-cells have a tendency to develop mutations that maintain BCL6; the end result is that B-cells grow out of control and transform into lymphomas.
Next, she showed that even small populations could efficiently purge deleterious mutations and maintain their overall level of fitness.
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