Sentence examples for mutation we injected from inspiring English sources

To investigate the dose dependence of RGEN-induced mutation, we injected varying amounts of Cas9 RNA and sgRNA no.

To test for a possible ultrastructural mistargeting of the channel complex as a consequence of the AAA mutation, we injected the RNA coding for rb-β1aAAA into relaxed zygotes and analyzed the orientation of DHPR particles opposite the RyR1 in 27 30 hpf larval tail muscles by freeze-fracture electron microscopy (Fig. 2).

In addition, to investigate whether the regional expression pattern of Pax3 is relevant in the context of the commonly occurring H3.3-K27M H3.3-K27Mutation, we injected Ntv-a;p53fl/fl mice withistoneells producing RCAS-PDGF-B, RCAS-H3.3-K27mutationCAS-Cre viruses [ 42].

To visualize the potential phenotypic effects of TRα mutations, we injected an mRNA mixture of the two TRα TALEN arms and mCherry into one cell of two cell-stage embryos to disrupt TRα on the left or right side of the tadpole body.

Furthermore, to exclude any adverse effect of blood circulation on the defects of gene expression in erythroid cells in both ribosomal mutation models, we injected rhodamine fluorescent dye into heart and analyzed the status of circulation at 3 dpf.

To obtain additional evidence that sec63 is disrupted by the st67 mutation, we rescued the mutants by injecting synthetic mRNA encoding wild-type sec63.

But for a mutation, we are all black.

To test whether the mutation in yap caused the coloboma phenotypes, we injected synthetic yap-GFP RNA into embryos from a cross between carriers and assessed phenotypic rescue.

To block Activin signals, we injected a dominant-negative Smad2 mutant (Smad2-P445H), wharborsrbors a point mutation in the MH2 domain that alters the structure and prevents C-terminal phosphorylation (Eppert et al., 1996).

When we injected aldh1a2um22 embryos with mRNA containing the aldh1a2um22 mutation, it could not rescue fin bud development (Figure 2 and Table 1).

We injected as an expression of individuality or secularisation.