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The MEK1 T55delinsRT mutation was uncovered specifically in M032R4 and was not detected in any of the other resistant tumors nor the pre-treatment tumor (Fig 4C).
In 1991, an APP gene mutation was uncovered in a family with autosomal dominant, early onset AD (Goate et al 1991).
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However, despite careful resequencing of all potential exons and intron exon junctions of TCF7L2 in 28 subjects with neonatal diabetes, and 17 with MODY (in whom other known causal genes had been excluded) no such mutations were uncovered.
A plethora of novel compound heterozygous NDUFS2 mutations were uncovered, including the c.875T>C (p.M292T) transition that was repeatedly identified in four unrelated white Caucasian infants with Leigh or Leigh-like syndrome.
The distinctive mutation IDH1 R132H was uncovered to be a strong prognostic biomarker for glioma patients.
To identify the molecular basis for the reduced NBN level, the whole NBN coding region was sequenced and the missense mutation p.R215W was uncovered in the hemizygous state.
The fossil was uncovered in Messel, Germany.
Her face was uncovered.
The coffin was uncovered.
The deception was uncovered.
The hoax was uncovered on 4 December.
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