Sentence examples for mutation was treated from inspiring English sources

The father carrier of the deleterious MT1-V124I mutation was treated for seasonal affective disorder with bright light therapy.

Interestingly, the father of this proband, who also carried the mutation, was treated with bright light therapy for seasonal affective disorder as well as his brother from whom DNA was not available.

A mutation was treated as dominant if its fraction reached more than 50% in the pool of viral quasispecies but did not reach complete substitution of original amino acid; e.g., a dominant reverse mutation is shown at position 114 in Figure 2B.

32 At disease progression, the patient whose tumor had this mutation was treated with gefitinib; this molecular alteration in EGFR was not associated with clinical response because the disease progressed after 4 weeks of treatment.

One other patient with a paternally inherited mutation was treated non-surgically with glucose polymer in feeds and octreotide and it was not determined whether he had a focal lesion or not.

Only one patient with harboring ALK translocation and EGFR mutation was treated by ALK inhibitor has been reported [ 17]. Lee et al. reported two ALK-positive and EGFR-mutant NSCLC patient who did not respond to EGFR-TKI but achieved a durable partial response to ALK inhibitor [ 17].

Jonathan Ledermann, professor of medical oncology at the University College London cancer institute and primary investigator of the pivotal olaparib clinical trial, said: "The positive Nice guidance for olaparib represents a turning point for how women with ovarian cancer and a BRCA mutation are treated by the NHS in England.

No patients with the mutation were treated with the latter two types of medication.

When the cells of the patient affected with the N273K mutation were treated for 5 days with increasing concentrations of glucosamine (Figure 5B) we found that the effect was proportional to the concentration of the inhibitor.

To understand whether similar effects could be also observed for other missense mutants the available primary cultures of skin fibroblasts from 9 MPS IIIC patients carrying missense HGSNAT mutations or a missense mutation in combination with a splice site or nonsense mutation were treated with glucosamine and assayed for N-acetyltransferase activity.

When HeLa cells stably expressing the R840C PAIS mutation were treated with the panel of agonists (Fig. 4, Table 1), they also demonstrated the ability to achieve increases in nuclear translocation similar to the wild type receptor (DHT: ↑ 21%; R1881: ↑ 29%; and, Mb: ↑ 29%), and at similar EC50 concentrations (DHT: 6.7 nM; R1881: 2.2 nM; and, Mb: 0.37 nM).