Sentence examples for mutation was smaller from inspiring English sources

But, unlike the filamentous viruses produced by wild-type (∼ 100 nm wide), the width of the filamentous particles produced by M1 mutation was smaller (Fig.  4C and D).

In male flies null mutation of the p53 gene increased mean life span by +12%95%5% bootstrap CI [4.92-14.50]; log-rank p-value ≈ 0), whereas the effect of heterozygous mutation was smaller, yielding mean life span increases of +5.5%95%5% bootstrap CI [2.15 - 7.53]; log-rank p-value ≈ 0).

The number of cases (five) without ATP1A3 mutation was small: none of these cases had documented ECG changes.

However, the study is limited as it was a retrospective analysis and the number of patients with a PIK3CA mutation was small.

With deep sequencing data, the variance of VAF for each mutation is smaller and relationships between the mutations become apparent.

Notably, the absolute changes in binding energy (ΔΔ Gbinding) mediated by the Val → Abu peptide mutation were smaller in the denaturant titrations (0.5 kcal/mol, 40 μM peptide) than in standard MST-based binding experiments (ΔΔ Gbinding ~ 1.3 kcal/mol).

This represents antagonistic pairwise epistasis between I572S and K43N: the cost of having both mutations was smaller than expected from their independent effects on the wild type (Additional file 2: Table S2).

The next most common type of mutation is small deletions (defined by HGMD as 20 bp or less), followed by splicing mutations and gross deletions.

If there are few mutations elsewhere in the gene (where they can be determined more reliably) the likelihood of a mismatch in the junction being due to a mutation is small.

The consensus sequence of the population of T7LME_2000 contained 17 mutations in addition to those found in T7 LME_200, indicating that evolution continued but that fitness effects per mutation were small by usual standards of T7 adaptation (Table 3).

This suggests that the size of the haplotype blocks associated with a causative QTL mutation are small compared to the size of the QTL confidence intervals obtained in our F2 segregation analysis.